Hepatic Encephalopathy

A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Also Known As:

Encephalopathy, Hepatocerebral; Encephalopathy, Portal-Systemic; Encephalopathy, Portosystemic; Fulminant Hepatic Failure with Cerebral Edema; Hepatic Coma; Hepatic Stupor; Hepatocerebral Encephalopathy; Portal-Systemic Encephalopathy; Coma, Hepatic; Comas, Hepatic; Encephalopathies, Hepatic; Encephalopathies, Hepatocerebral; Encephalopathies, Portal-Systemic; Encephalopathies, Portosystemic; Encephalopathy, Portal Systemic; Hepatic Comas; Hepatic Encephalopathies; Hepatic Stupors; Hepatocerebral Encephalopathies; Portal Systemic Encephalopathy; Portal-Systemic Encephalopathies; Portosystemic Encephalopathies; Stupor, Hepatic; Stupors, Hepatic; Encephalopathy, Hepatic; Portosystemic Encephalopathy

Digestive System Diseases: 1068
- Liver Diseases: 42767
  - Hepatic Insufficiency: 1080
    - Liver Failure: 8949
      - Hepatic Encephalopathy: 5889
Nervous System Diseases: 14737
- Central Nervous System Diseases: 4371
  - Brain Diseases: 16141
    - Metabolic Brain Diseases: 218
      - Hepatic Encephalopathy: 5889
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10634
  - Metabolic Brain Diseases: 218
    - Hepatic Encephalopathy: 5889

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Drug/Important Bio-Agent (IBA)